![]() The key pathophysiological features of MAA are alteration in hair cycle development, follicular miniaturization and inflammation. ![]() Normal levels of androgens are sufficient to cause hair loss in genetically susceptible individuals. A familial tendency to MAA and racial variation in the prevalence is well recognized, with heredity accounting for approximately 80% of predisposition. MAA is increasingly identified as a risk factor for arterial stiffness and cardiovascular disease. Although MAA is often regarded as a relatively minor dermatological condition, hair loss impacts self-image and is a great cause of anxiety and depression in some men. MAA occurs in a highly reproducible pattern, preferentially affecting the temples, vertex and mid frontal scalp. Male androgenetic alopecia (MAA) is the most common form of hair loss in men, affecting 30-50% of men by age 50.
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